The paper is aimed at studying the dependence of probability of International Space Station modules penetration for different space debris environment models and the calculation techniques used in practice. Two techniques (software) were used for calculation of the penetration probability: The Russian "SDPA-PP" code. The American "BUMPER" code. The following models were used as the data sources on space debris environment: SDPA-2000 and ORDEM2000 for "SDPA-PP" software and SSP-30425, ORDEM96 and SDPA-2000 for "BUMPER" software. The data on geometrical parameters as well as on wall and bumper parameters of modules play extremely important role in calculating the penetration probability. So, the coordinated unified data on aforementioned parameters and the coordinated equations for ballistic limit critical diameters (ballistic curves) were applied in all calculations. The following issues are presented in the paper: The features of the applied methods of penetration probability calculation. The comparative characteristics of the used space debris (SD) environment data. The detailed analysis of penetration probability estimates.